The Akuwaiseni Guest House Johannesburg is located in Melville. This is a trendy area of town which also offers convenient access to the Apartheid Museum, the Johannesburg Zoo and the Johannesburg Art Gallery. The hotel is convenient to a train station, located a few minutes' drive away. The Akuwaiseni Guest House Johannesburg provides its guests with transfers to the Johannesburg International Airport.

The rooms at the Akuwaiseni Guest House Johannesburg come in self-servicing and catered varieties. Kitchens are standard and are fully-equipped. Each room contains satellite television service, a maid service that cleans the room every morning, ceiling fans and pool towels. The private baths contain bathrobes and toiletries courtesy of the hotel.

The Akuwaiseni Guest House Johannesburg has amenities such as a pool and a spa onsite. The spa offers a complete line of reinvigorating services. There are cottages at the hotel where guests can either prepare their own meals or order a meal offered by the hotel. There is an onsite golf course available to guests, as well.